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RT @drGregBowman: What a spectacular week! #COVID19 @foldingathome paper in @NatureChemistry #DeepLearning paper in @NatureComms New grant from @NIH @justin_j_miller got a postdoc fellowship @CatieKnoverek got good reviews on a manuscript and so much good data from the rest of the lab! (Feed generated with FetchRSS) Afficher l’article complet

RT @drGregBowman: Topping off a great #InaugurationDay by getting the #COVID19 #vaccine. What a hope inspiring day! Hope everyone else will also get #vaccinated at their earliest opportunity. (Feed generated with FetchRSS) Afficher l’article complet

RT @foldingathome: Join all of us at FAH and @Schwarzenegger in saying 'hasta la vista baby!' to #COVID19 as we get the #vaccine! https://twitter.com/Schwarzenegger/status/1351973032953188352 (Feed generated with FetchRSS) Afficher l’article complet

A, l’épidémie de #COVID19 a incité de nombreuses personnes à participer à F@H pour essayer à leur niveau de lutter contre la pandémie B, les participants à F@H, on peut voir que la France est plutôt bien représentée C, comparaison entre les 10 plus gros supercalculateurs et F@H (Feed generated with FetchRSS) Afficher l’article complet

RT @foldingathome: @nvidia We have analyzed our dataset (capturing 0.1 seconds of simulation, the largest in history!) to identify over 50 novel pockets across many #COVID19 proteins! These “cryptic pockets” are candidates for targeting with antivirals. (Feed generated with FetchRSS) Afficher l’article complet

RT @drGregBowman: My 4-year-old: Dada, I don't like the bug (#coronavirus)! When will it go away?😿😿😿 Me: I don't know, but all of my science friends are working hard to make it go away. (Feed generated with FetchRSS) Afficher l’article complet

RT @foldingathome: To end #FAHPockets week, we feature the #COVID19 Nucleoprotein with bonus soundtrack (SOUND ON for the full effect). This video highlights how F@h data helps us identify more than cryptic pockets, we use it to find conformations and states that might tell us how a protein works! https://t.co/L3PwlH01gM (Feed generated with FetchRSS) Afficher l’article complet

RT @drGregBowman: Great progress capturing how the ferocious #COVID19 #Demogorgon (aka spike) opens its mouth to grab its human prey. Each step could present new therapeutic opportunities. Thanks to @foldingathome @Microsoft @Azure #AIforHealth @Mizimmer90! https://t.co/uys4es7r3i (Feed generated with FetchRSS) Afficher l’article complet

RT @foldingathome: Hooray for more #FAHPockets! Today we present a pocket found in the NSP13 helicase (spheres): https://t.co/4GJ1ddcHZY (Feed generated with FetchRSS) Afficher l’article complet

The best diagram of the #SARSCoV2 virus sucker, with its protein components, that I've seen Link to come later from accompanying @NEJM essaypic.twitter.com/7P2r9QjrL6 Afficher sur Twitter

Global organization @FoldingatHome is researching #COVID19 proteins that could help with designing therapeutics. This AI for Health grantee harnesses the collected power of millions of volunteers through Azure and GitHub. #MSBuildpic.twitter.com/f6c2XHqOg7 Afficher sur Twitter

Excited to share that we are studying SARS-CoV-2 Spike protein dynamics and its perturbations (if any) upon mutation. Thanks @bradyajohnston for a great illustration of our work! @FatihiSaman @Surabhi_CSB @deep_anshi @NidhiJatana A thread to explain our recent findingspic.twitter.com/Lgg0YLVIRG Afficher sur Twitter

One of the @drGregBowman lab’s go-to analyses for analyzing F@h trajectories is called Exposons! In this edition of #FAHPastSuccesses Porter and Moeder et al combined F@h data with experimental measurements to demonstrate the existence of a new pocket in beta-lactamase!pic.twitter.com/gRqs6hWcUi Afficher sur Twitter

Today’s #FAHMeetTheProteins features the Nucleoprotein RNA binding domain! https://www.biorxiv.org/content/10.1101/2020.03.06.977876v1.full …pic.twitter.com/CMkgn7jUWk Afficher sur Twitter

A lot of you have been eager for more work units, so we wanted to give you an overview of our process and a status update. We’re working hard to get more work servers up and running in response to our rapid growth in users. Stay tuned!pic.twitter.com/860T3z0jVb Afficher sur Twitter

We want to let you all know what proteins we are simulating, what they do, and what we hope to learn from these studies! We’ll call it #FAHMeetTheProteins Today’s protein is nsp10 from SARS and SARS-CoV2 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4162180/ …pic.twitter.com/8xyM5rlEGK Afficher l’article complet

The F@h team is working hard to generate as many new #COVID19 WUs as possible. In the meantime you may get a WU for another disease, and that’s okay! We care very deeply about addressing our current global health threat, but we also care about preventing future ones. Afficher l’article complet

Envie d'aider la recherche contre le Coronavirus grâce à votre ordinateur ? Rejoignez le projet Folding at Home simplement en installant un logiciel sur votre ordinateur. Plus de renseignement sur https://alliancefrancophone.org/dossiers/covid19 … Afficher l’article complet

With our new web site, we want to unify all of our web assets under the same url and same look (as much as possible). So, we've moved our blog to http://folding.stanford.edu/home/blog For now, we'll keep the old blog here, but we've moved the old posts, so eventually this site will go away as well. Voir l'article complet

Looks like everything is up, except for a single server (VSP07) and its VM's associated with it. This server is serving Core11 GPU clients, so those are off line at the moment. Our sysadmins are working on this now. Voir l'article complet

The networking seems to be up, but there are a few issues. They've got something basic going now and will resolve the remaining issues in the morning. We are running a stats update right now. Voir l'article complet

Looks like the servers are up and healthy, but there is an issue with the networking which central IT is working on. For now, we are in a holding pattern until the networking has been resolved. Voir l'article complet

The maintenance is moving along, but certain key machines are down during the move, most notably the main AS, GPU AS, and some key stats systems. We expect the maintenance to be completed in an hour or two. Voir l'article complet

One aspect which has dominated FAH for a decade is the continual push for new scientific approaches. This manifests itself in terms of new scientific cores. For example, the new GPU core (Core17) has brought huge speed improvements (especially to AMD GPUs) and involved a complete rewrite. A negative consequence of this continuous push for improvement and progress is that newer cores often are restricted to more advanced hardware. To help utilize as much power as is available to FAH, we tend to continue projects with older cores, but eventually, the science they can do becomes too limiting, and we must retire them. This is the eventual fate for all cores, but is most certainly an issue sooner for certain cores, especially cores11 and 78. While we don't have any specific end dates for either, we'd like to remind donors that those cores are reaching "end of life" status, and when they are retired, certain older hardware (eg CPUs that don't support SSE2 or older GPUs) won't be supported by FAH. The bottom line is that we're working to delay that as long as possible, but this post is a heads up that our support of those cores won't last a lot longer. If I had to guess, I'd say probably within a year or so they would be retired, maybe 2 years if the existing projects need additional data. As always, we'll give donors more information as we know it and try to give a more specific end date when we know it. Voir l'article complet